In recent years, the beauty and cosmetic industry has experienced a shift towards products which contain bioactive ingredients with the effects of medical drugs. Argireline-based dermal creams, lotions and ointments are among the emerging cosmeceuticals with promises for anti-wrinkle and anti-aging effects from the comfort of home, replacing the need for extensive botox, laser treatments and surgeries to achieve that youthful look.
What is argireline?
Argireline is an established and innovative product used in the cosmetic market as creams, lotions and ointments and is well-known for its anti-aging properties. It is a synthetic hexapeptide produced in the lab, which is composed of chains of amino acids and patterned from the N-terminal end of the protein SNAP-25.
It inhibits the movement of facial muscles, allegedly improving skin texture and tone. Research suggests that Argireline may not penetrate deep enough into the skin to consistently provide benefits.
Argireline is a synthetic hexapeptide peptide that is patterned from the N-terminal end of the protein SNAP-25 and has been shown to reduce the degree of facial wrinkles. It is reported to inhibit vesicle docking by preventing formation of the ternary SNARE complex and by interfering in catecholamine release. The anti-wrinkle efficacy of argireline has not been studied in Chinese subjects.
How does argireline reduce the effects anti-aging?
Argireline reduces periorbital wrinkles and prevents the formation of skin lines in a similar way the botulinum toxin (Botox) works, by inhibiting neurotransmitter release at the neuromuscular junction. When argireline is applied to the skin, it is absorbed into the body and its chemical composition causes the facial muscles to contract with less force. This diminishes the appearance of wrinkles and can smooth out fine lines that appear with aging. Argireline-based creams can be quite effective, and in some cases, users of argireline-based serums can experience as much as a 30% reduction in fine lines and wrinkles.
A randomized, placebo-controlled study by Wang, Y. conducted in 2013 has also shown that argireline reduced the depth of the wrinkles with a total anti wrinkle efficiency of 48.9% in 60 patients. When the same test was performed on mice, there were notable improvements in the morphology of skin tissue and the amount of Type Ⅰ collagen fibers increased while the amount of type Ⅲ collagen fibers decreased.
The total anti-wrinkle efficacy in the group with patients tested with argireline was 48.9 % whereas the efficacy was 0 % in the placebo group. The parameters of roughness were all decreased in the argireline group, while no decrease was observed in the placebo group.
Dr. TWL’s Oligopeptide vegetal capsules contain argireline. With its clinically proven anti-aging properties, our Oligopeptide capsules relaxes facial tension lines resulting in less noticeable fine lines and wrinkles.
Argireline. (2019, April 05). Retrieved from https://thedermreview.com/argireline/
The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study. Wang Y, Wang M, Xiao S, Pan P, Li P, Huo J. Am J Clin Dermatol. 2013 Apr;14(2):147-53.
The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects. Wang Y, Wang M, Xiao XS, Pan P, Li P, Huo J. J Cosmet Laser Ther. 2013 Apr 22.
The study of cellular cytotoxicity of argireline – an anti-aging peptide. Grosicki M, Latacz G, Szopa A, Cukier A, Kieć-Kononowicz K. Acta Biochim Pol. 2014;61(1):29-32. Epub 2014 Mar 17.
In my previous articles, I have talked about cosmeceuticals and the importance of incorporating them in our daily routines. However, how do we enhance the skin absorption of these cosmeceuticals? Here I will be talking about the limitations of topical formulations and how we can overcome them to ultimately achieve the results that we desire.
The problem with topical formulations for your skin
The outermost layer of the skin, called the stratum corneum, acts as a natural barrier. It prevents foreign material from entering our system, shields us against environmental factors and prevents excessive water loss. The skin is a formidable barrier to the passage of substances into and out of the body, but it can be manipulated to allow it to become a viable pathway for drug administration.
Drug products applied to the skin’s surface penetrate the skin layers to a certain extent, where they can exert their effects. This is the case for topical formulations for treatment of skin disorders such as acne, dermatitis, and psoriasis. However, very few drugs are suitable for delivery by the topical route, as passive penetration through the skin is limited to very small molecules (<500Da), which are neutral and relatively lipophilic. Some considerations of dermatologists would be the vehicle of the topical, specifically if it is in a lotion, cream or ointment form, in increasing order of absorption and effectiveness. This however, is often limited by user preferences, with ointment formulas (more efficacious) deemed cosmetically less acceptable.
The skin is the largest organ of the human body, comprising 15% of body weight and therefore its use to deliver medicine to the body is not a new concept by any means. Advancements made by modern science are improving the skin’s potential as a route for drug administration. Dermatologists are at the forefront of research relating to transdermal drug delivery, given the unique accessibility of the largest organ of the body.
Owing to the drawbacks of topical formulations, transdermal patches have been developed to improve drug delivery through the skin and this is an area that my team has actively researched in the last year as an adjunct to our cosmeceutical formulations.
I have always been interested in finding new methods to allow my patients to achieve optimal results from our cosmeceuticals, thus in this article I shall share some tools which I employ in my clinical practice to achieve optimal absorption of cosmeceutical active ingredients.
Wet Wrap/Occlusion Skin Therapy & Facial Masks
A well known method employed by dermatologists to treat severe eczema known as wet wrap is actually a simple process involving applying a wet textile together with topical medications to skin, to increase absorption of skincare. An example of how and when wet wraps are used— during particularly intense eczema flares with severe itch or pain, wet wrap therapy rehydrates and enhances the absorption of topical medications applied on the skin. The fabric wraps are soaked in water and applied to the affected skin on the body. Wet wraps are best done after bathing, moisturising and applying topicals, then left overnight.
Wet wraps work via 3 different ways:
● Cooling — as water gradually evaporates from the bandages this cools the skin and helps relieve inflammation, itching and soreness
● Moisturising — cosmeceuticals covered over with wet bandages are deeply absorbed in to the skin to provide a longer-lasting moisturising effect
● Absorption — enhanced absorption of any topicals into both the superficial and deeper layers of skin where inflammation is present
Facial sheet masks work in a similar way, on the basis of occlusion. This means that when there’s a topical which is applied on the skin and also in contact with something moist such as a sheet mask, there is increased absorption of the topicals by the skin. In my practice, whenever I want to increase absorption of cosmeceuticals and moisturisers that are dispensed to patients, I would advise them to apply a wet cotton sheet (as a wet wrap) on to their face to increase absorption.
I would consider masking as something which is very good to do if you are already diligent with other aspects of skin health such as cleansing and applying cosmeceuticals. Using a face mask would deliver moisture and clinically active ingredients to the skin—so it is important to look out for ingredients such as glycerin, ceramide and hyaluronic acid, as well as evidence-based antioxidants for anti-ageing such as oligopeptides, vitamin C ( I use sodium ascorbyl phosphate which is a neutral, rather than acidic form of vitamin C, that has minimal skin irritation). Here’s a tip, use a cosmeceutical moisturiser like the Radiance Fluide™ and increase your skin’s absorption by applying it on damp skin, plus a soft wet cotton towel over it.
Performing a facial massage, such as with the aid of a facial roller before application of cosmeceuticals could increase the skincare absorption, leading to better effects of the anti- aging skincare. Local massage is an established treatment method of improving surgical scars, by stimulating blood flow and improving wound healing. A peer-reviewed study published in a medical journal Complementary Therapies in Medicine led by author Miyaji Akane at the Institute for Liberal Arts, Tokyo Institute of Technology (Tokyo Tech) and colleagues at Tokyo Healthcare University and the Research and Development Center, MTG Co. Ltd. in 2019 had examined the effects of using a facial roller on facial skin and blood flow. The study concluded that there was significantly increased vascular (blood vessel) dilation with use of the facial massage roller. This means that there will be increased absorption of any cosmeceuticals applied on the face following the massage.
My recommendation would be manual rather than electric facial rollers as the latter may cause excessive pressure and irritation (being automated) and is also dependent on user training as well as the manufacturer’s settings, with a potential risk of overheating of electric components. Manual facial massage is a self-regulated process as the user can immediately sense irritation and apply just the right amount of pressure.
Transdermal medications (usually in the form of a patch) are a little more modern and complex. Great strides in transdermal drug delivery have been made since the first transdermal drug was approved by the FDA in 1979.
Transdermal drugs bring medication through the skin, to the bloodstream. Once in the bloodstream, the ingredients circulate and take effect at a targeted location. Medication is delivered steadily and can be stopped simply by removing the patch. Since your body doesn’t have to digest the medicine through the stomach, a higher concentration reaches the bloodstream. The medication permeates the skin in a controlled fashion thus attaining more ready levels of the drug in the body.
The science behind polymers and transdermal drug delivery systems
Polymers are vital in a transdermal drug delivery system. Systems for transdermal delivery are assembled as a multilayered polymeric laminates consisting of a drug reservoir sandwiched in between 2 polymeric layers:
● An outer impervious backing — prevents the loss of drug
● An inner polymeric layer — functions as an adhesive and rate-controlling membrane There are 3 types of transdermal drug delivery systems:
● Reservoir systems
In this system, the drug reservoir is embedded between a backing layer and a rate-controlling membrane.
● Matrix Systems
In this system, the drug reservoir is either dispersed in an adhesive polymer or in a hydrophilic or lipophilic polymer matrix.
● Micro-reservoir Systems
This system is a combination of the above 2 systems. The drug reservoir is formed by suspending the drug in an aqueous solution and then dispersing the solution in a lipophilic polymer to form thousands of microscopic spheres of drug reservoirs.
Polymers used in transdermal delivery systems should have biocompatibility with the drug and other components of the system. They should also provide consistent, effective delivery of a drug throughout the product’s intended shelf life.
An example of a common polymer used are silicones, also known as polysiloxanes, made of many repeating units of siloxanes. Siloxanes are chains of alternating silicon and oxygen atoms that are often combined with carbon and/or hydrogen. Medical grade silicones are silicones that undergo specific testing for their biocompatibility and have been deemed appropriate to be used for medical applications. Topical silicone therapy is often used by plastic surgeons and dermatologists to treat and heal scars.
Key considerations of a polymer patch used for transdermal drug delivery would be —conformability of the material to be applied to irregular skin or scar surfaces, sensitive regions such as the face/eye area and the overall durability and biocompatibility of medical grade polymers.
The process of skin ageing relates to the ability of the body’s natural healing processes. The same cells which are activated during cell injury are the ones which lose function with ageing, and are responsible for loss of collagen, elastin and the overall loss of volume and elasticity of skin. Specifically, antiageing cosmeceuticals target and stimulate cells known as fibroblasts, which are best thought of as the “soldiers” of wound healing which produce collagen to seal up injured or damaged skin. Injury to the skin occurs over a gradual process in the case of ageing, due to the slowing of one’s biological clock and photodamage.
For the last year, my team and I worked with a material scientist to develop a transdermal delivery patch, the QRASER™ Transdermal absorption patch, launched in July 2019. This patch works via a matrix system of drug delivery. In this system, the drug reservoir is dispersed in an adhesive polymer matrix. The transdermal delivery patch uses a unique polymer technology that mimics the natural hydration and homeostasis of the skin barrier, to enhance cosmeceutical absorption. The focus is on improving absorption via optimisation of the skin healing microenvironment.
The result? Healthy collagen production thus reducing fine lines and wrinkles.
In conclusion, cosmeceuticals in the arena of dermatologist-led skincare research will be increasingly prominent in the next decade of “smart skincare”. This should be emphasised along with understanding of how these topicals work, the limitations of skincare absorption and potential technologies such as transdermal delivery patches which can optimise the anti-ageing benefits of cosmeceutical skincare.
Dr. Teo Wan Lin, founder and medical director of TWL Specialist Skin & Laser Centre, is one of Singapore’s prominent dermatologists specialising in medical and aesthetic dermatology. She is also the founder of Dr.TWL Dermaceuticals which specialised in cosmeceutical skincare. In July 2019, a material science arm Dr.TWL Biomaterials was launched focusing on novel biomaterials for skin and hair application. Click here for the links to our product and here to read more about Dr.TWL Dermaceuticals and here to read more about Dr.TWL Biomaterials.
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Dermal fillers are minimally invasive mainstay cosmetic treatments used to help return the appearance of volume and youth to ageing skin. Volume deficiency, scars, wrinkles, lip augmentation (plumping), facial sculpting and contouring are common facial concerns targeted by dermal fillers.
This guide will tell you everything you need to know about them: how they work, the choices of products on the market, and their possible side effects on your body and skin.
What are dermal fillers?
Before starting on dermal fillers, we need a brief understanding of how the face changes as we age. Over time, the thickness and elasticity of our skin decreases, and our faces loses fat. Soft tissues sag, facial muscles weaken, and the outermost layer of skin wrinkles.
Enter fillers. Dermal fillers help restore lost volume to your face and add lift.
Types of dermal fillers
The classifications of dermal fillers vary according to their properties. Fillers are categorized based on their biodegradability, how long it takes before the filling substance is absorbed by the body, and the duration of a treatment’s effect.
Early attempts to use fillers for facial rejuvenation relied on dermal fat or collagen fillers. However, the effectiveness of fat as a filling agent was risky as a number of variables were involved. These included the method and type of fat harvested, both of which could cause inconsistent absorption rates by the body. There could also be significant side effects including prolonged swelling, internal bruising and cause infections. Bovine (cattle) collagen, the first collage filler used, also had limited success due to its short duration of effect (3-4 months) and potential risk of allergic reaction.
Human-based collagen has since been developed but demand for collagen remains low compared to more effective filling agents.
These are fillers that provide temporary or semi-permanent effects as they gradually degrade and get absorbed by the body. Common biodegradable fillers are collagen, hyaluronic acid, calcium hydroxyapatite and poly-L-lactic acid.
Naturally present in our skin and connective tissues, hyaluronic acid is a key structural component that stabilizes cellular structures and binds collagen and elastic fibers. Hyaluronic acid remains as the most widely used dermal filler due to its ease of use, safety and minimal side effects.
When hyaluronic acid is injected into the skin, it combines with the natural hyaluronic acid found in our body. Due to its hygroscopic nature (ability to absorb water from surroundings), hyaluronic acid binds to water quickly, creating volume that lasts for 6 to 12 months before degrading into the body. It also induces new collagen formation, a desirable quality as our bodies gradually stop producing collagen in our late twenties.
Poly-L-lactic acid (PLLA)
A synthetic, biodegradable polymer of the alpha-hydroxyl-acid family (natural acids found in food), poly-L-lactic acid (PLLA) is another common filling agent. Its safe profile enables PLLA to be actively used in other medical applications such as in dissolvable stiches or soft tissue implants.
PLLA triggers mild inflammation to promote the formation of collagen and tissue fibers. The accumulation of collagen creates volume at the site of injection. Over time, PLLA breaks down into lactic acid and is metabolized to carbon dioxide or incorporated into glucose molecules.
Calcium hydroxylapatite (CaHA)
CaHA is a synthetic compound with a chemical structure that resembles a component found in our bones and teeth. Treatment with CaHA is safe and will not cause allergic reactions. When injected into skin tissues, our body gradually absorbs CaHA, inducing new collagen to be produced. Such an effect typically lasts about 15 months or longer.
CaHA breaks down into calcium and phosphate ions before finally being excreted by the body.
Injecting silicone into the face adds volume directly and immediately and also triggers collagen production that adds to the effect. Silicone is favoured for its stable chemical structure, ease of use, low cost, and long-lasting effects. As a non-biodegradable filler, silicone stays in your body once it is injected.
However, the use of silicon in cosmetic treatments is controversial due to its potential to cause long-term complications such as abnormal swelling, blindness or nerve damage. Issues can also arise from poor injection technique, the amount of silicone used and differences in silicone grades. For these reasons, it is strongly recommended you get your fillers done only by a trained dermatologist.
Warnings and alternatives
Administered professionally and with the proper technique and expertise, a dermal filler comes with minimal side effects. However, with many different rejuvenation treatments available, it’s important you consult a trusted dermatologist for a professional assessment before commencing treatment.
For those who prefer plumping effects without an injection, go for Dr TWL’s Hyaluronic Acid serum. As a skincare ingredient, hyaluronic acid draws moisture from its surroundings and keeps the skin well-hydrated; it is able to hold over 1,000 times its own weight in water. This gives a desirable plumping effect and improves fine lines and wrinkles without the needles.
Have you ever woken up groggy from less than six hours of sleep and felt your skin is looking unwell? Ever wonder why?
How lack of sleep impacts your skin
Dehydrates the skin
The skin barrier works as a shield against environmental threats and prevents excessive water loss. When you don’t get enough sleep, your skin barrier can weaken and your levels of transepidermal water loss (TEWL) can be higher. TEWL is the amount of water lost to external environments via evaporation. Increased water loss dries out our skin, which can cause skin scaling and increased desquamation or the shedding of the skin’s outermost cells.
Imagining your skin cells as bricks and the lipids/fats in between as mortar, dehydrated skin has a more ‘disorganised’ brick and mortar structure; this causes more light to bounce off the surface. In comparison, hydrated skin has an ‘organised’ structure, allowing more light to penetrate the skin and giving off a translucent appearance.
Your pores can also appear larger with the lack of rest. While you will not have an increased number of pores if you snooze less, increased skin scaling causes a coarser skin texture and can make pores appear enlarged.
Reduces immune system function
Sleep also plays a role in restoring the body’s immune system function. Any change in the immune response may affect collagen production and lead to impaired skin integrity.
Inflames the skin
Sleep deprivation also triggers increased levels of inflammatory cytokines, which in turn modify the structures of collagen molecules. Collagen gives the skin its elasticity and flexibility. Assembling into a dense network of fibres, collagen holds the dermis layer together and protects the skin from external sources such as bacterial agents or ultraviolet radiation. Lower collagen levels manifest as thinner and wrinkled skin.
Ages your skin
Poor sleepers may experience uneven pigmentation, fine wrinkling, skin laxity, loss of facial fat and benign skin growths.
Chronic poor quality of rest is also associated with accelerated intrinsic ageing. Intrinsic ageing results from factors inherent in chronological ageing such as metabolic oxidative stress.
Stress is also a likely factor inherent in the lack of sleep. In response to stress, your brain releases an excess of stress hormones called glucocorticoids. This hormone causes negative effects on nearly all body tissues and accelerates the aging process. Glucocorticoids also inhibit lipid production, which eventually weakens skin integrity.
Regain your skin’s well-rested radiance
If you covet a seemingly translucent, pore-less look, it’s no surprise that we suggest you catch up on your sleep.
However, while you’re trying to change your snooze habits, providing rich hydration to your skin can also help compensate for some of your sleep loss. Apart from a moisturizer, a good boost of hydration also can come from an effective hyaluronic acid serum.
Alpha hydroxy acids (AHA) are naturally-occurring compounds possessing unparalleled benefits to the skin and extensively used in a dermatologist’s office. Most AHAs are non-toxic and are often present in food and fruits, thus also known as fruit acids.
The types of AHA used commonly for cosmetic purposes are glycolic acid and lactic acid. Glycolic acid, found in sugar cane, has the smallest molecule of all the AHAs and is the most widely used acid in skincare. Lactic acid is present in sour milk and tomato juice and can be found in our bodies as a byproduct of metabolic processes.
Certain types of AHA have lipophilic (ability to dissolve in lipids/fats) side groups in its chemical structure such as mandelic acid and benzylic acid. Such acids are more soluble in lipids over the conventional water-soluble AHAs, thus are often used for oily and acne-prone skin.
Uses as a peeling agent
AHAs are commonly used in peeling procedures as a short intense exposure to the acid produces benefits to the skin. A chemical peel is the application of one or more chemical exfoliating agents to the skin, and by exerting a controlled epidermal injury, it allows regeneration of new epidermal and dermal tissue. Such treatments are often used to treat skin disorders and conditions for aesthetic improvement.
Using controlled higher concentrations of AHAs, application to the skin for short times can achieve substantial desquamation (skin peeling). This renewal of skin cells is useful in anti-ageing, reducing hyperpigmentation and improving radiance. It is important to have a chemical peel conducted by an accredited dermatologist, to prevent uneven peeling and dermal wounding.
In contrast to other peeling agents, such as phenol or salicylic acid, most of the AHAs are nutritive and physiologic.
Whilst most skin types can opt for an AHA chemical peel, it is imperative to first seek assessment by an accredited dermatologist who will cater the peel, such as the acid type, strength, frequency and duration, for variability of individual skin conditions. Performed properly by a trained dermatologist, risk of scarring from a chemical peel is drastically reduced. The level of expertise in administering peels ensures a good outcome.
Prior to the actual application of the chemical peel substance, the skin will need to be thoroughly cleansed to remove oil and debris before being rinsed and dried.
Treatment with Chemical Peel
The peeling agent (AHAs) will be applied on the skin using an applicator or a brush. The duration of allowing the peeling agent to be in contact with the skin varies according to the skin’s conditions as assessed by the dermatologist. With superficial peels, some sensation of heat and stinging may be experienced, before the peeling agent is neutralized (where applicable) and thoroughly cleansed off after the duration of contact recommended by the dermatologist.
The chemical peel treatment is completed at our clinic with application of a hydrating Amino Acid Masque to soothe and calm the skin post-peel. Additional post peel care requires the use of sunscreens and other photoprotective agents, due to sun sensitivity post-treatment. It should be noted that regular application of sunscreen is advocated as it can reduce sun damage and aggravating of skin conditions.
How does a chemical peel work?
For superficial peels, the acid causes breakdown and decreases cohesiveness of corneocytes, that are found at the outermost part of the epidermis. Desquamation occurs, allowing renewal from lower epidermal layers. By weakening and ‘ungluing’ the cells in the inner stratum layer, it leads to uniform exfoliation of the outermost stratum layers.
With a low PH, most acid peels need to be properly neutralized to prevent acidification of the skin. To avoid burning, AHA peels are neutralized with basic salts such as sodium bicarbonate or sodium hydroxide.
A chemical peel does not compromise the barrier structure or integrity of the skin, as the mechanism of action of AHAs on the skin is a more targeted action for epidermal skin renewal.
As a treatment that improves skin texture and counters the effects of ageing, chemical peels continue to be relied on for various skin conditions. It is also safe for the skin and human health in general, as extensively tried and tested by dermatologist’s. A range of AHA formulations and concentrations are available for the dermatologist to administer therapy according to the patient’s requirements.
Speak to your dermatologist today for a tailored experience.
Planning for your big day? Yes, you have finally found your dress, and you are beyond ecstatic. Only to be bogged down with issues about the wedding venue, sending invitations, your flowers and finding suitable photographers. Nevertheless, don’t let all the stress get to you, and your skin! You would certainly want to walk down the altar with glowing radiant skin after all, so here’s an expert guide to skincare routine just in time for your D-Day.
When it comes to wedding beauty, women tend to get more hardworking with their regular masking and night-time skincare routine. Changing your skincare routine two or three months before your big day can give you ample time for your skin to reach its optimal condition. Apart from religiously looking after your skin, keep a lookout for your lifestyle habits. Start exercising, take regular meals, and cut down on the alcohol. Make sure you are sleeping well; a lack of sleep will certainly play no help in skin recovery.
Treat those dark spots and wrinkles with a chemical peel
If a major skincare concern such as hyperpigmentation has been troubling you, visit a dermatologist to see what your options are. You can go for chemical peels to reduce the appearance of sun spots, fine lines, wrinkles, enlarged pores and acne scars.
Performed by a dermatologist, a chemical peel treatment improves the appearance of the skin by gently stimulating the top layer of the skin cells by applying a solution made of fruit-derived acids. Such acids include alpha-hydroxy acids, glycolic acid, lactic and salicylic acid. This treatment can stimulate the skin to regenerate, revealing a taut, baby-smooth skin.
Chemical peels are more cost-effective compared to other treatments such as lasers, and more beneficial for the skin than beautician facials. A thorough evaluation is required before proceeding with a chemical peel. It is not recommended to undergo chemical peels with aestheticians or beauticians. In Singapore, only medical doctors have access to the prescription-level peel strength required to allow results.
Consult your dermatologist for an assessment for a chemical peel treatment plan catered for best results leading up to your wedding day. After the treatment, you may experience a reaction similar to sunburn where redness can be seen. Commence your chemical peel treatment plan at least three months prior to the wedding, for time buffer in particular, for your skin to be optimally renewed ahead of time and avoid any potential redness.
Common beauty concerns before a wedding include back and chest acne. Being in a wedding dress means your back and neck area will most likely be exposed. Acne at these areas as well as the face, may be well managed and controlled with chemical peels by your dermatologist, for your most radiant self to be presenting on the big day. Do avoid the sun as much as you can and stick to complete sun protection, such as sunscreen and sunglasses to reduce the sun damage.
Makeup may have varying results on camera, so it’s probably unwise to count on that to capture your best on the wedding day. To ensure that radiant glow on photos, a little more effort now on your skincare routine, could be a very worthwhile investment to yield super glowing and almost flawless (if not flawless) skin on camera on your big day.
Pre-wedding skincare routine at home
Go for a rich, nourishing serum like the Elixir-V™ Total Recovery Serum for hydrating, lifting and tightening of your face for the sculptured V-face look. Using such a serum in your skincare routine is perfect for pampering the facial skin before your big day. The Larecea™ extract found in the serum supports skin regeneration and helps in reversing signs of aging.
Hyaluronic acid is also included to preserve and replenish moisture, working to keep our skin hydrated. Antioxidants such as Resveratrol protects the skin against sun damage and lowers incidence of skin disorders. Infused in the Elixir-V™ is also Oligopeptides, which are essentially protein molecules that can help to repair and lift the skin, giving brides the perfect V-face look.
Vitamin C should also be an imperative component in your pre-wedding skincare routine. Try the Vitá C Gold™ Serum if you are guilty of living without Vitamin C previously, as a proprietary formulation with a super-stabilized form of Vitamin C that delivers more anti-oxidant efficacy than the conventional ascorbic acid which deteriorates quickly.
Vitamin C is a superstar ingredient that helps fade pigmentation and uneven skin tone. The ability of this vitamin to aid the skin in healing and resist acne, keeps it a top favourite ingredient, and you can also bid farewell to errant sun spots and scars from your youth. It also protects skin cells from damage, keeping the skin healthy and bright for your wedding day.
Other miscellaneous tips you will need
It’s a proud moment, and you have the right to flaunt it. Everyone will be throwing glances at your rings, so ransack your vanity drawers for that spare hand cream you never used. Toss it in your hand bag and perhaps another on your bedside table. Start a habit of lathering your hand cream on, and that will be one problem crossed off the list.
And if you are rocking a backless wedding dress, you would want to keep your back acne far away. It can be nerve-racking, but if you start a skincare routine early, you can still bring back the sexy back. Apply a minimum SPF30 sunscreen liberally, as clothing does not block all the UV light. Keep your sunscreen lightweight with like the SunProtector™ to avoid the greasy feel whilst ensuring that the sun does not cause more damage or breakouts.
For mild acne, even on the back, commencing a diligent skincare routine with cosmeceuticals could yield very tangible results ahead of your wedding day. For best results and in cases of more severe acne, however, consult your dermatologist for peels, topicals and a complete treatment plan to help in skin renewal, to unclog pores and reduce back acne.
Lastly, to avoid looking greasy on camera, dust some good setting powder to limit the shine while still keeping the glow.
The word anti-aging alone turns many heads. Living in a beauty-centric society, we are pressurised to maintain our youth. Although it’s a natural process to age, once we hit the big 3-0, we are told to maintain our youth with an onslaught of anti-aging products that promotes and stimulates collagen production. Then there is the whole array of anti-aging treatments such as a filler or botox procedure. You can’t really blame yourself for getting sucked into this black hole and there’s nothing really wrong about wanting to look young.
Are you looking for the fountain of youth? Look no further. Fillers are actually becoming a popular option for those wanting a youthful look. In comparison to anti-aging skincare, injectables such as fillers offer an almost instant youthful look and are fairly safe and natural looking when done right at the right place.
Although our skin is remarkable in protecting our bodies from the outside world and repairing itself every day, with age, lifestyle and environmental factors such as sun damage, smoking and poor diet, the condition of our skin deteriorates. This is inevitable. When it comes to giving your skin a refreshing and youthful appearance by giving it definition, firmness and a deep hydration, fillers are an effective method. Done by injecting a gel-like substance into lines and wrinkles, these injectables either fill or add volume to the sunken areas.
Hyaluronic Acid Filler
Hyaluronic acid is a common component that is used in fillers. Before you shrug at the term acids, know that hyaluronic acid is a component naturally found in the human body. Its sole function is to provide hydration and structure. Since skin hydration and structure depletes as we age, it is quickly removed from the body. By injecting these fillers, we are essentially introducing hydration and structure in the skin.
Lasting up to six to twelve months, these temporary fillers plumps up the eyebrow and temporal region, defines and contours the cupid’s bow, cheeks and jawline, smoothens out the under-eye hollows, facial creases and can even minimise the appearance of scars and other depressed creases.
Restylane is one of the many available injectables out there. Using a patented Non-Animal Stabilised Hyaluronic Acid (NASHA) technology, Restylane injectables are generally firmer for a more pronounced lifting capacity and targeted product integration. This delivers a longer lasting skin hydration. Its Optimal Balance Technology (OBT), ensures that the injectable is more evenly diffused in the injected area, creating a softer and more natural look.
Next question in mind would be what to expect before, during and after a filler procedure. First things first, always consult an accredited dermatologist or surgeon when getting a filler or any cosmetic surgery. Avoid going to any aesthetic spas or worse neighbourhood malls to get your fillers done. Hygiene and sanitary is pertinent when it comes to any corrective treatments, to avoid infections and side effects. Make sure you understand the procedure and don’t be afraid to ask any questions.
Always remember to inform the dermatologist or surgeon about your present medical condition and allergies. Avoid taking any medications such as panadol that may hasten bruising, or intoxicants such as alcohol, and stay hydrated. Always ask your dermatologist, or trained practitioner what type of filler you are getting injected with. Do some background research of it and make sure you are comfortable with being injected with that particular type of filler chosen for you. Instead of going for a cheaper alternative, choose the type of filler that is recommended by your dermatologist or surgeon, to avoid a botched procedure.
If you feel uncomfortable or uneasy during your filler procedure, voice out your concerns. As for post-procedure, expect minor bruisings. Hydration is key when it comes to healing. So drink up. Avoid using controlled substances such as cigarettes and alcohol immediately after the procedure. To avoid irritating the injected area, minimise makeup or external touch such as facials, pinching or scratching of the skin, high-intensity workouts and even sauna sessions. It is pertinent to abide by the post-procedure instructions given by your dermatologist or surgeon. Although minor bruisings can be expected, always report any signs of abnormality such as bumps, unevenness or unforeseen side effect to your dermatologist or surgeon immediately.
Regardless of the technique employed, skin resurfacing is a form of controlled, targeted injury to your skin. By stimulating your skin to heal from the injury, the new skin cells that form after would be smoother, tighter and more youthful. Skin resurfacing can be achieved through different techniques to treat different aspects of skin damage and conditions, mainly laser, dermabrasion and chemical peels.
Are you suitable for skin resurfacing?
These treatments can help skin that suffers from acne, damage from sun exposure, ageing effects, hyperpigmentation, scars and wrinkles. Any skin condition that you wish to treat likely has an appropriate treatment at your dermatologist, go for a professional diagnosis before having any skin resurfacing treatments done.
Before the peel, your face will be cleansed thoroughly to remove oil and to prep the skin for penetration. A gentle, medically formulated milk/fruit acid solution is applied, which removes the epidermis layer, allowing the acid to penetrate into the first layer of the dermis. Various acids can be used in different combinations to remove the surface layer of the skin. Note not all acids are the same nor are all chemical peels the same, best to have an accredited dermatologist assess and recommend the most suitable peel for your skin.
To smoothen scars and wrinkles, dermabrasion is a surgical technique that uses anesthesia and/or a freezing agent before smoothening skin surface irregularities. With a high-speed rotating brush, the surface layer of the skin will be removed till ideal results are obtained.
A wand is passed over your skin and emits a pulse of high-intensity light to damage the surface layers of the skin. The different invisible wavelengths of light stimulates various layers of skin for rejuvenation. Shield goggles will be provided to protect your eyes during the treatment.
Two types of lasers are commonly used in laser resurfacing: carbon dioxide and erbium. Both lasers work to vaporize damaged skin cells in the epidermis.
What can I expect after the treatment?
Follow-up care is essential to ensure a smooth progress for skin healing and resurfacing. Patients may experience uneven pigmentation of the skin at the treated area after the treatment, but this effect will subside when the skin restores its original level of pigment. Meanwhile, sunscreen is an absolute must to protect the skin as chemical peels along with other resurfacing treatments will render your skin temporarily more sensitive to the sun. At this stage, it is also imperative to use skincare catered for sensitive skin, which are dermatologist-tested, to mitigate risk of irritation and flare ups during the course of recovery post-treatment.
As a dermatologist, one of the first signs of ageing I observe shows in the eye area, what we call the peri-orbital or peri-ocular region. The commonest complaints I hear from my patients old or young are “Is there anything I can do for my eye bags, dark circles and eye wrinkles?” This is tricky because while so many spas, medi-spas, aesthetics providers and skincare companies confidently brag about their treatments erasing eye wrinkles and waving eyebags goodbye, I often have to burst bubbles in my clinic when I tell my concerned patients their hopes may be misplaced in a single miracle product which probably doesn’t exist.
In my practice, I use a multi-dimensional approach to work the aged eye area — a combination of skin resurfacing (nitrogen plasma over laser for sensitive areas such as the eye region), injectables like botulinum toxins, dysport and Botox. This, in conjunction with an eye cream that I formulate for my patients to use on a daily basis for before and after care, with specific active ingredients to brighten, tighten, moisturise and anti-age periorbital skin, besides being tested for safety and efficacy to complement medical aesthetics treatments around the eye area.
Men and women alike are affected by concerns of ageing and looking older, there’s nothing vain about wanting to look like a younger version of one’s self. In fact, it has been shown that your skin starts to age at around the age of 25. Main areas of wrinkles are at the forehead, nose, mouth and especially around the eyes. Eye wrinkles are often noticed first and more evident as the skin in this area is thinner, making it susceptible to wrinkling. Regardless of gender, you are prone to getting wrinkles so start taking care of your skin to maintain your youthful appearance!
What is Plasma Skin Regeneration?
It is a non-laser treatment that uses a device to convert nitrogen gas into plasma energy, to rejuvenate skin by improving facial lines, wrinkles and pigmentation caused by photoaging. This technology offers a wide variety of single pulse energy levels with different options of frequency that can most efficiently improve the precision of plasma delivery. This function allows accurate temperature irradiation to drastically improve topical drug delivery for a variety of dermatological indicators.
Personalisation of settings to cater to different patients is available, as patients’ skin conditions differ in terms of downtime and receptivity to treatments. Through deep tissue re-modelling, the energy delivered by plasma skin regeneration is non-fractionated. This allows for even energy absorption, ensuring the consistency in treatments done to the skin. The high energy also supports significant skin tightening. With deep tissue re-modelling and accelerated healing, plasma skin regeneration usage is versatile and effective.
The handpiece first releases the nitrogen plasma pulses.
This causes it to transfer thermal energy to the skin, allowing for controlled heating of the tissue.
The controlled duration of the pulse and temperature then allows the treatment to happen optimally.
This then leads to the possibility of treatments of many dermatological conditions due to the carefully controlled time frame.
Nitrogen plasma technology has been tested and backed by evidence. It has over 3 years of pre-clinical and clinical testing, 16 separate studies conducted, more than 450 clinical study treatments which proved to cause no scarring or pigmentation, and one year of clinical histology. This intense and detailed level of testing is uncommon in the industry, whilst clinically proven to perform skin resurfacing and regeneration using plasma energy.
Drug Delivery Effect
There are many treatable indicators like anti-aging effects, pore size reduction, wrinkle reduction, skin tightening, stretch marks reduction, acne scar reduction and more. However, one key effect is the drug delivery effect. When the skin is exposed to the nitrogen plasma, the permeability of the skin increases. This allows for better absorption of the drug, enhancing drug delivery and making the drug more effective during and after treatment.
Plasma skin regeneration converts nitrogen gas into the fourth state of matter, plasma energy. It then emerges from the handpiece in controlled pulses and causes rapid heating of tissue. This allows for the transmission of thermal energy to the tissue.
The treated photodamaged skin layers undergo controlled thermal modification without additional harm. This allows for speedy healing and a natural layer of protection for the skin. At high temperature and energy, the skin epidermis breaks down and sheds, but only after a new healthier skin layer forms beneath. Plasma skin regeneration is non-invasive and will not cause any open wounds.
Treats the Whole Skin Structure
Plasma skin regeneration can treat the entire skin structure. It ensures that the entire skin surface is regenerated and produces conditions favourable for optimal results. It is associated with neocollagenesis and neoelastogenesis. Neocollagenesis is the process of making more collagen while elastogenesis refers to the mechanisms that drive elastic fiber formation for our skin.
Ideal for Eyelids Treatment
The skin around our eyes, our eyelids, are especially sensitive and thinner than the rest of our skin. Thus, not all treatments are suitable to prevent eye wrinkles and eye bags. However, plasma skin regeneration, with its precision safety and efficacy, is suitable for treatment of the eyelids to reduce wrinkles and achieve an anti-aging effect, whereas previous technologies might be less safe for sensitive thin eyelid areas or even deliver inconsistent and ineffective results. In addition, due to the significant skin tightening effect from skin regeneration, deepening of the eyelids (with a look of deeper-set double eyelids) is also achieved.
Long Lasting Effects
Plasma skin regeneration has been proven to show neocollagenesis and reduce elastosis (abnormal elastic tissue in the skin which is a result of excessive sun exposure). Elastosis can cause your skin to have wrinkles and even pigmentation. The nitrogen plasma technology has post treatment effects that can last for more than a year.
With its reliable and advanced technology, plasma skin regeneration can produce anti-aging and long-lasting effects with its non-invasive methods, helping you to achieve a bright and youthful appearance.
People have been increasingly conscious about aging and the effects of aging on appearance. Skin aging will cause facial wrinkles and decreased collagen. Maintaining a youthful appearance seems to be the trend and many have resorted to skin treatments. There are many treatments like chemical peels, fractional laser and more but recently, ultrasound has been used in new treatments. HIFU and Ultherapy are examples of ultrasound treatments. It has been introduced as non-invasive and effective in having anti-aging effects on the skin.
What is High-Intensity Focused Ultrasound (HIFU) Sygmalift?
High-Intensity Focused Ultrasound also known as HIFU Sygmalift, is used for rejuvenation, lifting and tightening of the facial skin. Research has been done to demonstrate the efficacy of HIFU Sygmalift. It has been found that HIFU Sygmalift is a safe and effective method for facial skin tightening. It can be used not only to improve skin texture, but also contour the upper arms, knees and thighs. Besides facial skin, it can be used for other parts of your body.
How does HIFU Sygmalift work?
HIFU mainly causes cellular damage and reduces volume of the designated area by coagulation and generating instant microthermal lesions. This is done by using high frequency ultrasound waves targeted at the tissue area without causing any damage to the skin epidermis and surrounding tissues. The targeted skin tissues get heated up which causes cells to be activated, generating new collagen to produce a skin lifting and anti-aging effect.
What is Ultherapy?
Ultherapy is a new Food Drug Administration (FDA) approved treatment that tightens and lift facial skin. The treatment is mainly for the eyebrow, chin and neck area but can be used anywhere where the skin is lacking tightening. Follow up treatments are recommended once a year to maintain the effects. The procedure has been used as it is non invasive and hence does not require anesthetic or sedation.
However, it has been said to be painful and it would be better for some to use local anesthetic. It has been said to have no foreign substances or drastic changes but achieves to improve the health of the cells beneath your skin surface to result in a subtle, natural and healthy effect on the outside.
How does Ultherapy work?
Ultherapy is different from the common laser techniques that target the outer layer of the skin. It penetrates the surface and transmits energy to the deeper skin layers. This way, it causes damage to the collagen layers to stimulate more collagen production as the cells are tricked into repairing the collagen. It uses ultrasound technology which has been used in fat burning treatments. With collagen production, it produces skin tightening and anti aging effects.
How are HIFU Sygmalift and Ultherapy different?
HIFU Sygmalift and Ultherapy sound similar in terms of their methodology. Both use ultrasound treatment, a popular choice for non invasive and non-surgical face lifting and tightening treatments. Their main goal is to produce anti-aging effects, helping you to preserve your youthful look. However, there are still some small differences between the two which can impact your decision is choosing the most suitable treatment.
Extent of Pain
One of the main complaints about ultherapy treatment is that it is known to be painful and some people require local anesthetic. However, HIFU Sygmalift is mainly painless because it uses fractionated HIFU. Instead of traditional HIFU techniques which use one concentrated beam, HIFU Sygmalift breaks up the beam into fractions and penetrates the skin at precise extents. People who use HIFU Sygmalift may feel a small sense of tolerable pain but it is definitely less painful that Ultherapy.
Extent of Skin Penetration
HIFU Sygmalift targets the dermis and connective tissues to stimulate collagen production. Meanwhile, Ultherapy can penetrate deeper even into the muscle tissues, which is why some people feel pain. However, both result in skin tightening and lifting effects.
Post Treatment Maintenance
For Ultherapy, most people may see visible results even after the first or second session. To follow-up, they are recommended to go for treatments once a year to maximise the effects. On the other hand, HIFU Sygmalift is used once a month to maintain your skin. Patients of HIFU Sygmalift are recommended to use anti-aging products that contains peptides to complement the treatment, supporting a gentler type of treatment.
Both HIFU Sygmalift and Ultherapy use similar technology and methods with very subtle differences. However, these differences can make a big impact on your comfort with the treatments. Both methods are still safe, striving to produce anti-aging effects on your skin. With the similarities and differences explained, you can now make the best decision for yourself and choose the treatment that suits you the most.